Purified Anti-Human ROR1 Antibody[DA009] (AN008660P)
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For research use only.
| Alternate Names | Inactive tyrosine protein kinase transmembrane receptor ROR1, MGC99659, Neurotrophic tyrosine kinase receptor related 1, OTTHUMP00000010573, OTTHUMP00000010574, OTTMUSP00000008344, receptor related 1, Receptor tyrosine kinase like orphan receptor 1, RGD1559469, ROR 1, RP11 24J23.1, Tyrosine kinase like orphan receptor 1, Tyrosine protein kinase transmembrane receptor ROR1, Tyrosine-protein kinase transmembrane receptor ROR1, ROR, receptor-related, Inactive tyrosine-protein kinase transmembrane receptor ROR, NTRKR, dJ537F, ROR1, NTRKR1, dJ537F10.1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1 |
| Clone | |
| Verified Samples | Verified Samples in FCM: NCCIT cells |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Immunogen | Recombinant Human ROR1 protein |
| Abbre | ROR1 |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Mouse IgG2b, κ |
| Isotype Control | Purified Mouse IgG2b, κ Isotype Control[MPC-11] |
| Applications |
FCM
|
| Research Areas | Neuroscience;Signal Transduction;Intracellular Kinases;Receptor Tyrosine kinases |
| Cellular Localization |
Membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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